Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment. Issue 6 (27th May 2013)

• Record Type: Journal Article
• Authors: Dlugolenski, Daniel; Jones, Les; Tompkins, S. Mark; Crameri, Gary; Wang, Lin‐Fa; Tripp, Ralph A.
• Is Part Of: Influenza and other respiratory viruses. Volume 7:Issue 6(2013:Nov.)
• Page Start: 900
• Page End: 903
• Publication Date: 2013-05-27
• Subjects: Influenza -- Periodicals; Respiratory infections -- Periodicals; Virus diseases -- Periodicals; Influenza, Human -- Periodicals; Respiratory Tract Diseases -- Periodicals; Virus Diseases -- Periodicals; Grippe -- Périodiques; Appareil respiratoire -- Infections -- Périodiques; Maladies à virus -- Périodiques; 616.203
• DOI: 10.1111/irv.12128
• Languages: English
• ISSNs: 1750-2640

Abstract

<abstract abstract-type="main" id="irv12128-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Waterfowl are primary hosts for influenza A viruses (IAVs); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow‐shouldered bats were shown to be hosts of an IAV, thereby constituting a potential novel reservoir. We show that <italic>Pteropus alecto</italic> kidney cells (PaKi) are susceptible to infection and sustain replication of A/WSN/33 (H1N1) and A/Vietnam/1203/04 (H5N1). Importantly, we show that co‐infection of PaKi cells results in novel reassortants.</p> </abstract>