Patients with penile cancer and the risk of (pre)malignant cervical lesions in female partners: a retrospective cohort analysis. (26th July 2013)

• Record Type: Journal Article
• Authors: de, Roderick E.; Heideman, Danielle A.M.; Kenter, Gemma G.; van, Marc; van, Harm; Horenblas, Simon
• Is Part Of: BJU international. Volume 112:Number 7(2013:Oct.)
• Page Start: 905
• Page End: 908
• Publication Date: 2013-07-26
• Subjects: Genitourinary organs -- Diseases -- Periodicals; Genitourinary organs -- Surgery -- Periodicals; Urology -- Periodicals; 616.6
• DOI: 10.1111/bju.12237
• Languages: English
• ISSNs: 1464-4096

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="bju12237-sec-0001" sec-type="section"> <title>Objective</title> <p> <list id="bju12237-list-0001" list-type="bullet"> <list-item> <p>To determine if female partners of patients with penile cancer have more cervical lesions and neoplasia than would be expected from population‐based data.</p> </list-item> </list> </p> </sec> <sec id="bju12237-sec-0002" sec-type="section"> <title>Patients and Methods</title> <p> <list id="bju12237-list-0002" list-type="bullet"> <list-item> <p>We included all consecutive patients with primary penile carcinoma in the period 2004–2010.</p> </list-item> <list-item> <p>Results of Dutch cervical cancer screening were used to consider (pre)malignant cervical lesions in female partners of patients with penile cancer.</p> </list-item> </list> </p> </sec> <sec id="bju12237-sec-0003" sec-type="section"> <title>Results</title> <p> <list id="bju12237-list-0003" list-type="bullet"> <list-item> <p>In all, 206 women were included.</p> </list-item> <list-item> <p>Gynaecological information was available in 195 women: Papanicolaou test (PAP) smears were normal were in 129 partners, 10 smears were abnormal (5.1%, 95% confidence interval 2.5–9.2).</p> </list-item> <list-item> <p>PAP2 was found in five, PAP3a in two, PAP3b in two women and PAP4 in one woman.</p> </list-item> <list-item> <p>Colposcopy in two women with PAP3b showed cervical intraepithelial neoplasia grade 3 in both.</p> </list-item> <list-item> <p>This prevalence was not different from baseline results in the general Dutch population.</p> </list-item> </list> </p> </sec> <sec id="bju12237-sec-0004" sec-type="section"> <title>Conclusion</title> <p> <list id="bju12237-list-0004" list-type="bullet"> <list-item> <p>Female partners of patients with penile cancer did not show more premalignant cervical lesions than in the general population.</p> </list-item> </list> </p> </sec> </abstract>