Dimethylformamide Catalyzed Synthesis of Novel Heterocycles—Their Characterization and Antimicrobial Evaluation. (29th March 2013)

• Record Type: Journal Article
• Authors: Dabholkar, Vijay V.; Patil, Sunil R.; Pandey, Rajesh V.
• Is Part Of: Journal of heterocyclic chemistry. Volume 50:Number 2(2013:Mar.)
• Page Start: 403
• Page End: 407
• Publication Date: 2013-03-29
• Subjects: Heterocyclic compounds -- Periodicals; 547.59
• DOI: 10.1002/jhet.1073
• Languages: English
• ISSNs: 0022-152X

Abstract

<abstract abstract-type="main" xml:lang="en" id="jhet1073-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p id="jhet1073-para-0002">Indandione <bold>1</bold> was brominated to yield 2‐bromoIndandione <bold>2</bold>, which further reacted with substituted thiocarbamides, carbamides, 2‐aminothiophenols, 2‐aminophenol, and triazole to furnished 3‐substituted aniline‐2‐thia‐4‐aza‐6, 7‐benzo‐8‐oxo‐bicyclo[3.3.0]‐1(5), 3‐octadiene <bold>3</bold>, 3‐substituted aniline‐2‐oxa‐4‐aza‐6, 7‐benzo‐8‐oxo‐bicyclo[3.3.0]‐1(5), 3‐octadiene <bold>4</bold>, 2‐Thia‐5‐aza‐9‐oxo‐3, 4‐(3′‐substituted) benzo‐7, 8‐benzo‐bicyclo[4.3.0]‐1(6) nonene <bold>5</bold>, 2‐oxa‐5‐aza‐9‐oxo‐(3, 4)‐(7, 8)‐dibenzo‐bicyclo[4.3.0]‐1(6) nonene <bold>6</bold>, 3′‐substituted‐(1′, 2′, 4′)triazolo[5, 6‐b][indeno(2, 3‐e)]‐1, 3, 4‐thiadiazine <bold>7</bold>, respectively. The structures of compounds were elucidated on the basis of spectral techniques, further the representative compounds were screened for their antimicrobial activity.</p> </abstract>