Impact of heart magnetic resonance imaging on chelation choices, compliance with treatment and risk of heart disease in patients with thalassaemia major. (16th August 2013)

• Record Type: Journal Article
• Authors: Origa, Raffaella; Danjou, Fabrice; Cossa, Stefano; Matta, Gildo; Bina, Patrizio; Dessì, Carlo; Defraia, Elisabetta; Foschini, Maria L.; Leoni, GiovanBattista; Morittu, Maddalena; Galanello, Renzo
• Is Part Of: British journal of haematology. Volume 163:Number 3(2013:Nov.)
• Page Start: 400
• Page End: 403
• Publication Date: 2013-08-16
• Subjects: Hematology -- Periodicals; Blood -- Diseases -- Periodicals; 616.15
• DOI: 10.1111/bjh.12517
• Languages: English
• ISSNs: 0007-1048

Abstract

<abstract abstract-type="main" id="bjh12517-abs-0001"> <title>Summary</title> <p>This study aimed to verify the impact of heart magnetic resonance imaging on chelation choices and patient compliance in a single‐institution cohort as well as its predictive value for heart failure and arrhythmias. Abnormal cardiac T2* values determined changes in treatment in most subjects. Heart T2* was confirmed to be highly predictive over 1 year for heart failure and arrhythmias. The choice of chelation regimens known to remove heart iron efficiently was not sufficient by itself to influence the risk. Compliance with treatment had a more remarkable role.</p> </abstract>