Detection of skin cancer margins in Mohs excisions with high‐speed strip mosaicing confocal microscopy: a feasibility study. (10th October 2013) - Larson, B.
Abstract What's already known about this topic? Fluorescence confocal mosaicing microscopy is an emerging technology for imaging of nuclear and morphological detail and assessing tumour margins directly in fresh Mohs excisions, without the need for frozen section processing. Basal cell carcinoma margins have been detected with a sensitivity of 96·6% and a specificity of 89·2%. What does this study add? A new and faster approach called strip mosaicing confocal microscopy has been developed, towards potentially routine implementation at the bedside. Preliminary assessment demonstrates both sensitivity and specificity of 94% for detecting skin cancer margins.