Alcohol consumption is associated with reduced risk of Type 2 diabetes and autoimmune diabetes in adults: results from the Nord‐Trøndelag health study. Issue 1 (13th December 2012)

• Record Type: Journal Article
• Authors: Rasouli, B.; Ahlbom, A.; Andersson, T.; Grill, V.; Midthjell, K.; Olsson, L.; Carlsson, S.
• Is Part Of: Diabetic medicine. Volume 30:Issue 1(2013:Jan.)
• Page Start: 56
• Page End: 64
• Publication Date: 2012-12-13
• Subjects: Diabetes -- Periodicals; 616.462
• DOI: 10.1111/j.1464-5491.2012.03713.x
• Languages: English
• ISSNs: 0742-3071

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="sec-sum-1" sec-type="section"> <p>Diabet. Med. 30, 56–64 (2013)</p> </sec> <sec id="abs1-1" sec-type="section"> <title>Abstract</title> <p> <bold>Aims </bold> We investigated the influence of different aspects of alcohol consumption on the risk of Type 2 diabetes and autoimmune diabetes in adults.</p> <p> <bold>Methods </bold> We used data from the Nord‐Trøndelag Health Survey (HUNT) study, in which all adults aged ≥ 20 years from Nord‐Trondelag County were invited to participate in three surveys in 1984–1986, 1995–1997 and 2006–2008. Patients with diabetes were identified using self‐reports, and participants with onset age ≥ 35 years were classified as having Type 2 diabetes if they were negative for anti‐glutamic acid decarboxylase (<italic>n</italic> = 1841) and as having autoimmune diabetes if they were positive for anti‐glutamic acid decarboxylase (<italic>n</italic> = 140). Hazard ratios of amount and frequency of alcohol use, alcoholic beverage choice, and binge drinking and alcohol use disorders were estimated.</p> <p> <bold>Results </bold> Moderate alcohol consumption (adjusted for confounders) was associated with a reduced risk of Type 2 diabetes in men, but not in women (hazard ratio for men 10–15 g/day 0.48, 95% CI 0.28–0.77; hazard ratio for women ≥ 10 g/day 0.81, 95% CI 0.33–1.96). The reduced risk was primarily linked to consumption of wine [hazard ratio 0.93, 95% CI 0.87–0.99 (per g/day)]. No increased risk was seen in participants reporting binge drinking or in problem drinkers. The results were also compatible with a reduced risk of autoimmune diabetes associated with alcohol consumption [hazard ratio 0.70, 95% CI 0.45–1.08 (frequent consumption) and hazard ratio 0.36, 95% CI 0.13–0.97 (2–7 g/day)].</p> <p> <bold>Conclusions </bold> Moderate alcohol consumption associates with reduced risk of both Type 2 diabetes and autoimmune diabetes. A protective effect of alcohol intake may be limited to men. High alcohol consumption does not seem to carry an increased risk of diabetes.</p> </sec> </abstract>