The effect of estrogen in a man with Parkinson's disease and a review of its therapeutic potential. (1st October 2013)

• Record Type: Journal Article
• Authors: Adams, Chris; Kumar, Rajeev
• Is Part Of: International journal of neuroscience. Volume 123:Number 10(2013:Oct.)
• Page Start: 741
• Page End: 742
• Publication Date: 2013-10-01
• Subjects: Nervous system -- Periodicals; 612.805
• DOI: 10.3109/00207454.2013.797903
• Languages: English
• ISSNs: 0020-7454

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Estrogen has been implicated in controlling the pathogenesis and symptoms of Parkinson's disease (PD) in women. Here, we report a 53-year-old male with PD who underwent estrogen therapy with estradiol (E2). Within a month, he exhibited increased dyskinesias. His medication was reduced by 35% from a levodopa equivalent dose (LED) of 820–535 over three months, which overall improved his motor fluctuations and dyskinesias. Therefore, E2 therapy could have therapeutic potential in males with PD.</p> </abstract>