Regulation of connexin‐ and pannexin‐based channels by post‐translational modifications. (17th July 2013)

• Record Type: Journal Article
• Authors: D'hondt, Catheleyne; Iyyathurai, Jegan; Vinken, Mathieu; Rogiers, Vera; Leybaert, Luc; Himpens, Bernard; Bultynck, Geert
• Is Part Of: Biology of the cell. Volume 105:Number 9(2013:Sep.)
• Page Start: 373
• Page End: 398
• Publication Date: 2013-07-17
• Subjects: Cytology -- Periodicals; Electron microscopy -- Periodicals; 571.6
• DOI: 10.1111/boc.201200096
• Languages: English
• ISSNs: 0248-4900

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="boc201200096-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Post‐translational modifications (PTMs) affect the regulation and localisation of connexin (Cx) and pannexin (Panx) proteins, which form large conductance channels, functioning as mediators of communication between neighbouring cells via gap junction channels and/or hemichannels. Hereby, PTMs influence the assembly, trafficking and function of Cx‐ and Panx‐based channels in normal cell biology and pathophysiology. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36nqw9rx" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>