Sarcoidosis and Sjögren's syndrome: clinical and salivary evaluation. (9th March 2013)

• Record Type: Journal Article
• Authors: Mansour, Mohammed J.; He, Cixin; Al‐Farra, Sharif T.; Khuder, Sadik A.; Wright, John M.; Kessler, Harvey P.; Hinton, Robert J.; Al‐Hashimi, Ibtisam
• Is Part Of: Journal of oral pathology & medicine. Volume 42:Number 8(2013:Sep.)
• Page Start: 594
• Page End: 599
• Publication Date: 2013-03-09
• Subjects: Dentistry -- Periodicals; Teeth -- Diseases -- Periodicals; 617
• DOI: 10.1111/jop.12057
• Languages: English
• ISSNs: 0904-2512

Abstract

<abstract abstract-type="main" xml:lang="en" id="jop12057-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jop12057-sec-0001" sec-type="section"> <title>Background</title> <p>Sarcoidosis and Sjögren's syndrome are two different diseases; however, when affecting the salivary glands, both diseases exhibit similar clinical signs and symptoms, which often complicates the diagnosis. The purpose of this study was to investigate the possibility of using salivary electrophoresis to differentiate between the two diseases.</p> </sec> <sec id="jop12057-sec-0002" sec-type="section"> <title>Methods</title> <p>Saliva was collected from patients with sarcoidosis and patients with Sjögren's syndrome. Salivary flow rate, total protein, and <italic>electrophoretic profiles</italic> were examined.</p> </sec> <sec id="jop12057-sec-0003" sec-type="section"> <title>Results</title> <p>Mean salivary flow rate was 0.41 ± 0.07 ml/min/gland vs. 0.43 ± 0.07 ml/min/gland; total salivary protein was 130.0 ± 29.2 mg% vs. 104.0 ± 8.8 mg% for sarcoidosis vs. Sjögren's syndrome, respectively. No differences were observed in salivary flow rate, total salivary protein, or electrophoretic profile between patients with sarcoidosis and patients with Sjögren's syndrome (<italic>P </italic>=<italic> </italic>0.768, 0.718, and 1.000, respectively).</p> </sec> <sec id="jop12057-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Salivary protein electrophoresis does not appear to be useful to differentiate between sarcoidosis and Sjögren's syndrome.</p> </sec> </abstract>