Translationally related nearly identical molecules: 4‐methoxyphenyl 4‐O‐[6‐O‐acetyl‐2‐azido‐3‐O‐benzyl‐2‐deoxy‐4‐O‐(fluoren‐9‐ylmethoxycarbonyl)‐α‐D‐glucopyranosyl]‐2‐O‐benzoyl‐3‐O‐benzyl‐6‐O‐chloroacetyl‐β‐D‐glucopyranoside. (7th June 2013)

• Record Type: Journal Article
• Authors: Gainsford, Graeme J.; Schwörer, Ralf; Tyler, Peter C.
• Is Part Of: Acta crystallographica. Volume 69:Part 6(2013:Jun.)
• Page Start: 679
• Page End: 682
• Publication Date: 2013-06-07
• Subjects: Crystallography -- Periodicals; Crystals -- Periodicals; 548.05
• DOI: 10.1107/S010827011301367X
• Languages: English
• ISSNs: 0108-2701

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The title compound, C₅₉H₅₆ClN₃O₁₆, is an important dissacharide precursor to novel therapeutics for the treatment of Alzheimer's disease. It crystallizes with two independent enantiomerically identical molecules in almost exactly the same orientation in the cell, being one half cell‐edge apart. Apart from the conformation of a single benzyl group, the molecules are superimposable. They are bound efficiently using complementary C—H...O(carbonyl) hydrogen bonds, principally along the `duplicating' axis. The absolute configurations were determined.</p> </abstract>