Comparison of ThermoCool® Surround Flow Catheter Versus ThermoCool® Catheter in Achieving Persistent Electrical Isolation of Pulmonary Veins: A Pilot Study. (4th December 2012)

• Record Type: Journal Article
• Authors: BERTAGLIA, EMANUELE; FASSINI, GAETANO; ANSELMINO, MATTEO; STABILE, GIUSEPPE; GRANDINETTI, GIUSEPPE; SIMONE, ANTONIO DE; CALÒ, LEONARDO; PANDOZI, CLAUDIO; PRATOLA, CLAUDIO; ZOPPO, FRANCO; TONDO, CLAUDIO; IULIANO, ASSUNTA; GAITA, FIORENZO
• Is Part Of: Journal of cardiovascular electrophysiology. Volume 24:Number 3(2013:Mar.)
• Page Start: 269
• Page End: 273
• Publication Date: 2012-12-04
• Subjects: Blood vessels -- Physiology -- Periodicals; Electrophysiology -- Periodicals; Heart -- Physiology -- Periodicals; 612.1
• DOI: 10.1111/jce.12031
• Languages: English
• ISSNs: 1045-3873

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Persistent Electrical Isolation of Pulmonary Veins</bold>. <italic>Introduction:</italic> Aim of this study was to compare efficacy and safety of the new ThermoCool Surround Flow® catheter (SFc) versus the ThermoCool® (TCc) in achieving persistent circumferential electrical isolation of the pulmonary veins (PVs) in patients with paroxysmal atrial fibrillation (AF).</p> <p> <italic>Methods and Results:</italic> This multicenter, randomized, controlled study enrolled patients suffering from paroxysmal AF. Randomization was run in a one‐to‐one fashion between radiofrequency ablation by TCc or SFc. Aim of PVs ablation was documentation of electrical isolation with exit/entrance block recorded on a circular catheter. Among the 106 enrolled patients, 52 (49.0%) were randomized to TCc and 54 (51.0%) to SFc. Total volume of infused saline solution during the procedure was lower in the SFc than in TCc group (752.7 ± 268.6 mL vs 1, 165.9 ± 436.2 mL, P < 0.0001). Number of identified and isolated PVs was similar in the 2 groups. Number of PVs remaining isolated 30 minutes after ablation was higher in the SFc than in TCc group (95.2% vs 90.5%, P < 0.03), mainly driven by acute ablation result in the left PVs (96.1% vs 89.7%, P < 0.04). Complications were seldom and observed only in the TCc group (0% vs 3.84%, P < 0.03). At 6‐month follow‐up SFc patients reported a trend toward less AF recurrences compared to those in the TCc group (22.9% vs 27.0%, P = 0.69).</p> <p> <italic>Conclusion:</italic> PV isolation by SFc lowered the rate of left PV early reconnections and reduced the volume of infused saline solution while maintaining the safety profile of AF ablation. <italic>(J Cardiovasc Electrophysiol, Vol. 24, pp. 269‐273, March 2013)</italic></p> </abstract>