Synergism between narrowband ultraviolet B phototherapy and etanercept for the treatment of plaque‐type psoriasis. (8th July 2013)

• Record Type: Journal Article
• Authors: Calzavara‐Pinton, P.G.; Sala, R.; Arisi, M.; Rossi, M.T.; Venturini, M.; Ortel, B.
• Is Part Of: British journal of dermatology. Volume 169:Number 1(2013:Jul.)
• Page Start: 130
• Page End: 136
• Publication Date: 2013-07-08
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/bjd.12277
• Languages: English
• ISSNs: 0007-0963

Abstract

<abstract abstract-type="short" xml:lang="en" id="bjd12277-abs-0002"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>What's already known about this topic?</bold> </p> <p> <list id="bjd12277-list-0001" list-type="bullet"> <list-item> <p>Previous studies have reported that the combination of etanercept (ETN) with narrowband ultraviolet B (NB‐UVB) improves the therapeutic result in patients with psoriasis who were not satisfactorily responsive to ETN alone administered at dosages of 50 mg once or twice weekly.</p> </list-item> <list-item> <p>However, it is unclear if this combination is more effective than NB‐UVB phototherapy alone.</p> </list-item> </list> </p> <p> <bold>What does this study add?</bold> </p> <p> <list id="bjd12277-list-0002" list-type="bullet"> <list-item> <p>The combination of etanercept with NB‐UVB has a synergistic effect for clearing plaque‐type psoriasis previously unresponsive to ETN and NB‐UVB phototherapy alone.</p> </list-item> <list-item> <p>The clearance rate is very high in a very short time without short‐term adverse effects.</p> </list-item> </list> </p> <p> <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">See also the Commentary by Hönigsmann</ext-link> </p> </abstract>