FOXP2. Issue 5 (13th August 2013)

• Record Type: Journal Article
• Authors: Nudel, Ron; Newbury, Dianne F
• Is Part Of: Wiley interdisciplinary reviews. Volume 4:Issue 5(2013:Sep./Oct.)
• Page Start: 547
• Page End: 560
• Publication Date: 2013-08-13
• Subjects: Cognitive science -- Periodicals; 153.05
• DOI: 10.1002/wcs.1247
• Languages: English
• ISSNs: 1939-5086

Abstract

<abstract abstract-type="main" id="wcs1247-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p id="wcs1247-para-0001">The forkhead box P2 gene, designated <italic>FOXP2</italic>, is the first gene implicated in a speech and language disorder. Since its discovery, many studies have been carried out in an attempt to explain the mechanism by which it influences these characteristically human traits. This review presents the story of the discovery of the <italic>FOXP2</italic> gene, including early studies of the phenotypic implications of a disruption in the gene. We then discuss recent investigations into the molecular function of the <italic>FOXP2</italic> gene, including functional and gene expression studies. We conclude this review by presenting the fascinating results of recent studies of the <italic>FOXP2</italic> ortholog in other species that are capable of vocal communication. <italic>WIREs Cogn Sci</italic> 2013, 4:547–560. doi: 10.1002/wcs.1247</p> <p>For further resources related to this article, please visit the WIREs website.</p> </abstract>