Non‐invasive assessment of cardiac output at rest and during exercise by finger plethysmography. (3rd April 2013)

• Record Type: Journal Article
• Authors: Critoph, Christopher H.; Patel, Vimal; Mist, Bryan; Thomas, Martin D.; Elliott, Perry M.
• Is Part Of: Clinical physiology and functional imaging. Volume 33:Number 5(2013:Sep.)
• Page Start: 338
• Page End: 343
• Publication Date: 2013-04-03
• Subjects: Physiology, Pathological -- Periodicals; Diagnostic imaging -- Periodicals; 612
• DOI: 10.1111/cpf.12032
• Languages: English
• ISSNs: 1475-0961

Abstract

<abstract abstract-type="main" id="cpf12032-abs-0001"> <title>Summary</title> <sec id="cpf12032-sec-0001" sec-type="section"> <title>Aims</title> <p>We sought to determine the accuracy of finger plethysmography using pulse waveform analysis with brachial calibration for measurement of cardiac output during submaximal exercise by comparing it against an acetylene (C<sub>2</sub>H<sub>2</sub>) uptake technique.</p> </sec> <sec id="cpf12032-sec-0002" sec-type="section"> <title>Methods</title> <p>The study included 24 healthy volunteers (12 males, age 35 ± 8 years). Testing was performed on an upright cycle ergometer using an incremental protocol. Cardiac output measurements were performed at rest and during sub‐maximal exercise using a single breath C<sub>2</sub>H<sub>2</sub> uptake technique and continuously using finger plethysmography with brachial calibration.</p> </sec> <sec id="cpf12032-sec-0003" sec-type="section"> <title>Results</title> <p>Valid results at rest and during sub‐maximal exercise were achieved in 20 of 24 participants. Cardiac output at rest was 5·3 ± 1·1 and 5·2 ± 1·2 l min<sup>−1</sup> for finger plethysmography and C<sub>2</sub>H<sub>2, </sub> respectively, <italic>P </italic>= 0·712. Mean difference between techniques was −0·1 ± 0·5 l min<sup>−1</sup>. Cardiac output during submaximal exercise was 10·2 ± 2·3 and 10·3 ± 2·1 l min<sup>−1</sup> for finger plethysmography and C<sub>2</sub>H<sub>2, </sub> respectively, <italic>P </italic>= 0·898. Mean difference between techniques was 0·1 ± 1·5 l min<sup>−1</sup>. The overall correlation between finger plethysmography and C<sub>2</sub>H<sub>2</sub> data obtained during rest and exercise was <italic>r</italic><sup>2</sup> = 0·872, <italic>P</italic><0·0001. Mean rise in cardiac output during exercise was 4·9 ± 1·5 (finger plethysmography) and 5·1 ± 1·5 l min<sup>−1</sup> (C<sub>2</sub>H<sub>2</sub>), <italic>P </italic>= 0·64.</p> </sec> <sec id="cpf12032-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Finger plethysmography determined cardiac output values both at rest and during sub‐maximal exercise are comparable with those obtained using a single breath C<sub>2</sub>H<sub>2</sub> uptake technique.</p> </sec> </abstract>