Cytomegalovirus Retinitis in Immunocompetent Patients: Case Reports and Literature Review. (August 2013)

• Record Type: Journal Article
• Authors: Radwan, Alaa; Metzinger, Jamie Lynne; Hinkle, David M.; Foster, C. Stephen
• Is Part Of: Ocular immunology and inflammation. Volume 21:Number 4(2013)
• Page Start: 324
• Page End: 328
• Publication Date: 2013-08
• Subjects: Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.3109/09273948.2013.786095
• Languages: English
• ISSNs: 0927-3948

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p> <italic>Purpose</italic>: The purpose of this study was to examine 2 cases of cytomegalovirus (CMV) retinitis, occuring in 2 immunocompentent adult patients.</p> <p> <italic>Methods</italic>: Case selection and literature review.</p> <p> <italic>Results</italic>: Both patients cited significantly decreased vision despite systemic, topical, and/or local corticosteroid use. Neither patient was using high-dose immunosuppressant therapy at the time of diagnostic testing. Both patients exhibited confirmed CMV infection via polymerase chain reaction DNA testing. Oral antivirals were employed and have stabilized both patients.</p> <p> <italic>Conclusion</italic>: The cases described herein serve to inform ophthalmologists of the urgent need to include CMV in their differential when encountering an immunocompetent adult with significant comorbidities or with a history of previous exposure. Proper treatment is heavily reliant on proper diagnosis.</p> </abstract>