Ethnicity and age disparities in Ewing sarcoma outcome. (10th July 2013)

• Record Type: Journal Article
• Authors: Koohbanani, Bianca; Han, Gang; Reed, Damon; Zhao, Qing; Yi, Ding; Henderson-Jackson, Evita; Bui, Marilyn M.
• Is Part Of: Fetal and pediatric pathology. Volume 32:Number 4(2013)
• Page Start: 246
• Page End: 252
• Publication Date: 2013-07-10
• Subjects: Pathology, Molecular -- Periodicals; Pediatrics -- Periodicals; Molecular biology -- Periodicals; Pediatric pathology -- Periodicals; Fetal Diseases -- pathology -- Periodicals; Infant, Newborn, Diseases -- pathology -- Periodicals; Pediatrics -- Periodicals; 618.92007
• DOI: 10.3109/15513815.2012.721480
• Languages: English
• ISSNs: 1551-3815

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>This institutional retrospective review studied Ewing sarcomas from 1987–2011. Among 135 patients, 127 (19 Hispanic and 108 white/non-Hispanic) were analyzed (excluding small sample sized groups) finding 15% Hispanic, 85% non-Hispanic, 27% &lt;18 years, 21% &gt;40 years and 1–272 months follow-up (median 41). Age was significantly associated with overall survival (OS) (<italic><underline>p</underline></italic> = 0.01), whereby &lt;18 years had a higher probability of 5-year survival (OS 61%) than &gt;40 years (OS 37.6%). Ethnicity was marginally statistically significant (OS, <italic>p</italic> = 0.065); whereby median survival was clinically significant (white non-Hispanic 63 months and Hispanic 23 months). Hispanic ethnicity and older age are independent poor prognostic factors.</p> </abstract>