Two novel alleles at HLA‐B locus identified in two volunteer bone marrow donors by sequence‐based typing. (3rd November 2012)

• Record Type: Journal Article
• Authors: Frison, S.; Longhi, E.; Mantovani, M.; Malagoli, A.; De, A.; Piccolo, G.; Poli, F.
• Is Part Of: International journal of immunogenetics. Volume 40:Number 4(2013:Aug.)
• Page Start: 328
• Page End: 330
• Publication Date: 2012-11-03
• Subjects: Immunogenetics -- Periodicals; 571.9648
• DOI: 10.1111/iji.12011
• Languages: English
• ISSNs: 1744-3121

Abstract

<abstract abstract-type="main" id="iji12011-abs-0001"> <title>Summary</title> <p>Two novel human leucocyte antigen (HLA) class I alleles have been identified in two Italian individuals. HLA‐B*27:07:02 is identical to HLA‐B*27:07:01 except for a nucleotide substitution at position 846 (A‐&gt;G) resulting in a silent mutation. HLA‐B*35:206 differs from the most similar allele, HLA‐B*35:08:01, because of a single base mutation at position 149 (G‐&gt;C) causing an aminoacidic change at codon 26 from Gly to Ala.</p> </abstract>