Weight gain regardless of pre-pregnancy BMI and influence of fetal gender in response to labor induction in postdate pregnancy. (July 2013)

• Record Type: Journal Article
• Authors: Torricelli, Michela; Voltolini, Chiara; Conti, Nathalie; Bocchi, Caterina; Severi, Filiberto M.; Petraglia, Felice
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 26:Number 10(2013:Oct.)
• Page Start: 1016
• Page End: 1019
• Publication Date: 2013-07
• Subjects: Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.3109/14767058.2013.766712
• Languages: English
• ISSNs: 1476-7058

Abstract

<abstract> <title>Abstract</title> <p> <italic>Objective</italic>: To evaluate whether maternal weight and body mass index (BMI) and their increase throughout pregnancy are associated with the response to labor induction in postdate pregnancies.</p> <p> <italic>Methods</italic>: A total of 376 nulliparous women carrying singleton postdate pregnancies with unfavorable cervix were enrolled. We considered as primary outcome vaginal delivery within 24 h after induction, and outcomes were divided into responders (<italic>n</italic> = 258) and non-responders (<italic>n</italic> = 107) to the induction of labor to perform the statistical analyses.</p> <p> <italic>Results</italic>: In the total population of study, women who successfully delivered within 24 h differed significantly from the remaining patients in terms of maternal weight gain (<italic>p</italic> = 0.009) and BMI increase (<italic>p</italic> = 0.02) during pregnancy. In addition, males were significantly more (<italic>p</italic> = 0.005) than females among newborns of women not responding to induction of labor. In the multivariate analysis, maternal weight gain and fetal sex significantly influenced the induction response. The occurrence of a failed induction of labor was more likely in patients presenting a greater maternal weight gain (cut-off 12 kg) and male fetus.</p> <p> <italic>Conclusion</italic>: Weight gain over 12 kg regardless of pre-pregnancy weight and male fetal gender are two novel potential risk factors for the prediction of failure to induction of labor in postdate pregnancy.</p> </abstract>