Outcomes of central bisectionectomy for hepatocellular carcinoma. Issue 7 (21st November 2012)

• Record Type: Journal Article
• Authors: Gallagher, Thomas K.; Chan, Albert C.Y.; Poon, Ronnie T.P.; Cheung, Tan To; Chok, Kenneth S.H.; Chan, See Ching; Lo, Chung Mau
• Is Part Of: HPB. Volume 15:Issue 7(2013:Jul.)
• Page Start: 529
• Page End: 534
• Publication Date: 2012-11-21
• Subjects: Liver -- Diseases -- Periodicals; Biliary tract -- Diseases -- Periodicals; Pancreas -- Diseases -- Periodicals; 616.362005
• DOI: 10.1111/j.1477-2574.2012.00615.x
• Languages: English
• ISSNs: 1365-182X

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="hpb614-sec-0001" sec-type="section"> <title>Background</title> <p>Central bisectionectomy (resection of Couinaud segments IV, V and VIII) for malignant or benign disease poses a technical challenge to the surgeon but if feasible, has significant benefits in terms of conserving liver volume and options for future intervention. This study reviews a cohort of patients who underwent this procedure; outlines the indications, optimal operative technique as well as both short‐ and long‐term outcomes.</p> </sec> <sec id="hpb614-sec-0002" sec-type="section"> <title>Methods</title> <p>A retrospective review of a prospectively maintained database was performed. Pre‐operative clinicopathological data, operative details and post‐operative outcomes including overall and disease‐free survival were analysed.</p> </sec> <sec id="hpb614-sec-0003" sec-type="section"> <title>Results</title> <p>Between 1989 and 2009, 21 patients underwent a central bisectionectomy. All procedures were performed for hepatocellular carcinoma (HCC). All patients underwent a R0 resection with a median resection margin of 5 mm (1–15 mm). The 1‐, 3‐ and 5‐year disease‐free survivals were 65%, 34.8% and 34.8%, and the corresponding overall survival rates were 90.5%, 66.8% and 66.8%, respectively.</p> </sec> <sec id="hpb614-sec-0004" sec-type="section"> <title>Conclusion</title> <p>These data support the use of a central bisectionectomy in selected cases in the management of HCC. With the use of a meticulous operative technique and adherence to surgical oncological principles, satisfactory long‐term outcomes were achievable.</p> </sec> </abstract>