Ultrastructural Patterns of the Activated Cell Death Programs in the Human Brain. (April 2013)

• Record Type: Journal Article
• Authors: Pais, Viorel; Danaila, Leon; Pais, Emil
• Is Part Of: Ultrastructural pathology. Volume 37:Number 2(2013:Apr.)
• Page Start: 110
• Page End: 120
• Publication Date: 2013-04
• Subjects: Pathology, Cellular -- Periodicals; Ultrastructure (Biology) -- Periodicals; Diagnosis, Electron microscopic -- Periodicals; Microscopy, Electron; Pathology; 616.07582
• DOI: 10.3109/01913123.2012.751949
• Languages: English
• ISSNs: 0191-3123

Abstract

<abstract> <title>Abstract</title> <p>The authors analyzed by transmission electron microscopy (TEM) neurosurgical samples obtained from patients with cerebral tumors, neurotrauma, cerebral ischemia, Moyamoya disease, encephalitis, etc. Their observations concern a variety of dying cell types by different programmed death pathways, including apoptosis, paraptosis, autophagy, autoschizis, programmed necrosis, as well as combined and coexisting forms. This ample work pointed out not only the role of TEM in cell death diagnosis, but the biological differences in cell behavior and beneficial or detrimental effects of suicides for homeostasis, survival, or normal functioning of a tissue, like the integrated vascular tissue and brain parenchyma.</p> </abstract>