In Vivo Characterization of Healthy Oral Mucosa by Reflectance Confocal Microscopy: A Translational Research for Optical Biopsy. (April 2013)

• Record Type: Journal Article
• Authors: Contaldo, Maria; Agozzino, Marina; Moscarella, Elvira; Esposito, Salvatore; Serpico, Rosario; Ardigò, Marco
• Is Part Of: Ultrastructural pathology. Volume 37:Number 2(2013:Apr.)
• Page Start: 151
• Page End: 158
• Publication Date: 2013-04
• Subjects: Pathology, Cellular -- Periodicals; Ultrastructure (Biology) -- Periodicals; Diagnosis, Electron microscopic -- Periodicals; Microscopy, Electron; Pathology; 616.07582
• DOI: 10.3109/01913123.2013.776656
• Languages: English
• ISSNs: 0191-3123

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: To characterize <italic>in vivo</italic> microscopic features of healthy oral mucosa by noninvasive, real-time reflectance confocal microscopy (RCM).</p> <p> <italic>Material and Methods</italic>: One hundred healthy mucosal sites (38 lips, 24 cheeks, 10 gingivae, and 28 tongues) from 50 randomly selected volunteers were imaged by a commercially available <italic>in vivo</italic> RCM (Vivascope3000, Lucid, Rochester, NY). Morphological results were described and correlated with conventional histology.</p> <p> <italic>Results</italic>: Specific microscopic parameters (cellular morphology, anatomical structures features, architectural patterns) were identified by RCM for each mucosal site.</p> <p> <italic>Conclusions</italic>: RCM features reproducibility in different mucosal sites and subjects, which suggests that RCM can be an adjunct tool for clinical management in stomatology.</p> </abstract>