Serial measurements of high-sensitivity cardiac troponin T after exercise stress test in stable coronary artery disease. (June 2013)

• Record Type: Journal Article
• Authors: Axelsson, Anna; Ruwald, Martin Huth; Dalsgaard, Morten; Rossing, Kasper; Steffensen, Rolf; Iversen, Kasper
• Is Part Of: Biomarkers. Volume 18:Number 4(2013)
• Page Start: 304
• Page End: 309
• Publication Date: 2013-06
• Subjects: Biochemical markers -- Periodicals; 610.28
• DOI: 10.3109/1354750X.2013.776635
• Languages: English
• ISSNs: 1354-750X

Abstract

<abstract> <title>Abstract</title> <p> <italic>Objective</italic>: The aim was to assess serial measurements of high-sensitivity cardiac troponin T (hs-cTNT) post-exercise in patients with stable coronary artery disease (CAD).</p> <p> <italic>Methods</italic>: Twelve patients with positive coronary angiograms (CAD positives) and 12 controls performed an exercise stress test.</p> <p> <italic>Results</italic>: CAD positive had higher baseline and peak concentrations of hs-cTNT than controls. Significant increases in hs-cTNT were seen in both groups after exercise. In two-third of patients the peak in hs-cTNT was above the 99th percentile.</p> <p> <italic>Conclusion</italic>: hs-cTNT is higher in patients with stable coronary disease than in controls and exceeds the diagnostic cut-off value for myocardial infarction in a majority of patients with CAD after exercise.</p> </abstract>