Diagnostic accuracy of whole‐body diffusion‐weighted magnetic resonance imaging with 3.0 T in detection of primary and metastatic neoplasms. Issue 3 (7th January 2013)

• Record Type: Journal Article
• Authors: Akay, Sinan; Kocaoglu, Murat; Emer, Ozdes; Battal, Bilal; Arslan, Nuri
• Is Part Of: Journal of medical imaging and radiation oncology. Volume 57:Issue 3(2013:Jun.)
• Page Start: 274
• Page End: 282
• Publication Date: 2013-01-07
• Subjects: Radiology, Medical -- Periodicals; Radiology, Medical -- Australasia -- Periodicals; 616.0757
• DOI: 10.1111/1754-9485.12026
• Languages: English
• ISSNs: 1754-9477

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="jmiro12026-sec-1001" sec-type="section"> <title>Introduction</title> <p>To discuss the accuracy of the whole‐body diffusion‐weighted imaging with background body signal suppression (WB‐DWIBS) technique performed in the 3.0‐T system.</p> </sec> <sec id="jmiro12026-sec-1002" sec-type="section"> <title>Methods</title> <p>We studied 17 patients who underwent positron emission tomography (PET)/CT and WB‐DWIBS examinations for staging their diseases. The DWIBS pulse and echo‐planar imaging‐short T1 inversion recovery single‐shot pulse sequences were performed for WB‐DWIBS. A PET/CT scan was performed with 18‐fluorodeoxyglucose. The lesions were localised and counted in both of the examinations, and WB‐DWIBS was evaluated for the neoplastic tissue detection rate, while PET/CT was accepted as the reference standard modality.</p> </sec> <sec id="jmiro12026-sec-1003" sec-type="section"> <title>Results</title> <p>The WB‐DWIBS scan had a room occupation time of 32–35 min. All of the metastasis positive patients (<italic>n</italic> = 12) detected with PET/CT were also detected with WB‐DWIBS (100%). In our patient group, there were a total of 109 bone metastases on PET/CT scans, and 93 of them (85.3%) were demonstrated with WB‐DWIBS. We detected 128 metastatic lymph nodes on PET/CT, and 123 of them (96.3%) were demonstrated with WB‐DWIBS. There were a total of 17 liver metastases on PET/CT, and 15 of them (88.2%) were detected with WB‐DWIBS. There was no statistically significant difference between the two imaging modalities in detecting bone, lymph node and liver metastases (<italic>P</italic> > 0.05).</p> </sec> <sec id="jmiro12026-sec-1004" sec-type="section"> <title>Conclusions</title> <p>WB‐DWIBS is a non‐invasive technique that may successfully detect the spreading of the tumoural tissue in cancer patients when compared with PET/CT.</p> </sec> </abstract>