Accuracy and precision of CPET equipment: A comparison of breath-by-breath and mixing chamber systems. (January 2013)

• Record Type: Journal Article
• Authors: Beijst, Casper; Schep, Goof; Breda, Eric van; Wijn, Pieter F. F.; Pul, Carola van
• Is Part Of: Journal of medical engineering & technology. Volume 37:Number 1(2013)
• Page Start: 35
• Page End: 42
• Publication Date: 2013-01
• Subjects: Biomedical engineering -- Periodicals; Medical technology -- Periodicals; 610.28
• DOI: 10.3109/03091902.2012.733057
• Languages: English
• ISSNs: 0309-1902

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Cardiopulmonary exercise testing (CPET) has become an important diagnostic tool for patients with cardiorespiratory disease and can monitor athletic performance measuring maximal oxygen uptake <inline-graphic xlink:href="ark:/27927/pgg1mqcfvvs" mimetype="image" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Vo2<sub>; max</sub>. The aim of this study is to compare the accuracy and precision of a breath-by-breath and a mixing chamber CPET system, using two methods. First, this study developed a (theoretical) error analysis based on general error propagation theory. Second, calibration measurements using a metabolic simulator were performed. Error analysis shows that the error in oxygen uptake (<inline-graphic xlink:href="ark:/27927/pgg1mqcfw35" mimetype="image" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Vo2) and carbon dioxide production (Vco2<inline-graphic xlink:href="ark:/27927/pgg1mqcftkv" mimetype="image" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />) is smaller for mixing chamber than for breath-by-breath systems. In general, the error of the flow sensor <inline-graphic xlink:href="ark:/27927/pgg1mqcfwkw" mimetype="image" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />δV, the error in temperature of expired air <italic>δT<sub>B</sub></italic> and the delay time error <italic>δt</italic><sub>delay</sub> are significant sources of error. Measurements using a metabolic simulator show that breath-by-breath systems are less stabile for different values of minute ventilation than mixing chamber systems.</p> </abstract>