Subclinical Hypothyroidism after Vascular Complicated Pregnancy. (February 2013)

• Record Type: Journal Article
• Authors: van der Zanden, Moniek; Groot Hop-de, Rianne J.; Sweep, Fred CGJ.; Ross, H. Alec; Heijer, Martin den; Spaanderman, Marc EA.
• Is Part Of: Hypertension in pregnancy. Volume 32:Number 1(2013)
• Page Start: 1
• Page End: 10
• Publication Date: 2013-02
• Subjects: Hypertension in pregnancy -- Periodicals; Pregnancy -- Complications -- Periodicals; 618.3261
• DOI: 10.3109/10641955.2011.642435
• Languages: English
• ISSNs: 1064-1955

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p> <italic>Objective</italic>. Women with a history of vascular complicated pregnancy are at risk for developing remote cardiovascular disease. It is associated with underlying cardiovascular risk factors both jeopardizing trophoblast and vascular function. Subclinical hypothyroidism may relate to both conditions. <italic>Methods</italic>. In 372 women with a history of vascular complicated pregnancy, we assessed thyroid function. <italic>Results</italic>. Subclinical hypothyroidism was diagnosed in 73/372 women (19.6%). It occurred more often when pregnancy ended before 32 weeks of gestation (<italic>p</italic> = 0.008). <italic>Conclusion.</italic> In this cohort, subclinical hypothyroidism is more common after very preterm delivery. It may contribute to the elevated risk of remote cardiovascular disease.</p> </abstract>