Consumption of polyphenol-rich juar tea increases endothelium-bound extracellular superoxide dismutase levels in men with metabolic syndrome: link with LDL oxidizability. (June 2013)

• Record Type: Journal Article
• Authors: Uto-Kondo, Harumi; Ayaori, Makoto; Kishimoto, Yoshimi; Adachi, Tetsuo; Takiguchi, Shunichi; Yakushiji, Emi; Sasaki, Makoto; Komatsu, Tomohiro; Kondo, Kazuo; Ikewaki, Katsunori
• Is Part Of: International journal of food sciences and nutrition. Volume 64:Number 4(2013)
• Page Start: 407
• Page End: 414
• Publication Date: 2013-06
• Subjects: Food -- Analysis -- Periodicals; Nutrition -- Periodicals; 641.3
• DOI: 10.3109/09637486.2012.759185
• Languages: English
• ISSNs: 0963-7486

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Endothelium-bound extracellular superoxide dismutase (eEC-SOD), a major antioxidative enzyme in the vasculature, is involved in anti-atherogenesis by inhibiting low-density lipoprotein (LDL) oxidation. The objective was to investigate whether the polyphenol-rich juar tea had beneficial effects on LDL oxidation and eEC-SOD levels in patients with metabolic syndrome (MetS). A total of 20 men with MetS participated in a randomized cross-over trial, comparing consumption of five cups/day of juar tea with that of a polyphenol-poor tea, barley tea, for 4 weeks. Although there was no change in LDL oxidizability after consumption of either tea, juar tea significantly increased eEC-SOD levels by 16% (<italic>p</italic> &lt; 0.05), whereas barley tea significantly decreased levels by 15% (<italic>p</italic> &lt; 0.05). It is noteworthy that the changes in eEC-SOD were positively associated with those in LDL oxidizability after tea consumption (<italic>r</italic>² = 0.11, <italic>p</italic> &lt; 0.05). Tea polyphenols may provide anti-atherosclerotic effects by inhibiting LDL oxidation through EC-SOD bound to the endothelium.</p> </abstract>