Biological effects of static electric field: Plasma/serum proteome analysis of rats. (March 2013)

• Record Type: Journal Article
• Authors: Harutyunyan, Hayk; Artsruni, Gagik
• Is Part Of: Electromagnetic biology and medicine. Volume 32:Number 1(2013:Jan.)
• Page Start: 79
• Page End: 94
• Publication Date: 2013-03
• Subjects: Electrophysiology -- Periodicals; Electromagnetic Fields -- Periodicals; Electrophysiology -- Periodicals; Radiation, Nonionizing -- Periodicals; 574
• DOI: 10.3109/15368378.2012.708694
• Languages: English
• ISSNs: 1536-8378

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>The external static electric field (SEF) of man-made origin brings to the substantially increased SEF background in a human environment the biological activity of which is a moot question. The paper reports on rats blood plasma/serum proteome modifications by means of 1D polyacrilamide gel electrophoresis and clotting process alterations after the short- and long-term SEF exposures of 200 kV/m. The results indicate decrease of fast α1 and α2 globular proteins in plasma coinciding with clotting acceleration after the short-term SEF, and attenuation of clotting-dependent proteome modifications reflected with incomplete coagulation after the long-term SEF exposure. Increased lysozyme activity in serum unlike plasma was observed after both SEF exposures. Applied model of the high-voltage SEF environment indicates dependence of biological systems functioning on the external SEF.</p> </abstract>