Childhood Recurrent Urinary Tract Infection in Southern Thailand. (February 2013)

• Record Type: Journal Article
• Authors: Vachvanichsanong, Prayong; Dissaneewate, Pornsak; McNeil, Edward
• Is Part Of: Renal failure. Volume 35:Number 1(2013)
• Page Start: 66
• Page End: 71
• Publication Date: 2013-02
• Subjects: Chronic renal failure -- Periodicals; Acute renal failure -- Periodicals; Uremia -- Periodicals; 616.614005
• DOI: 10.3109/0886022X.2012.741647
• Languages: English
• ISSNs: 0886-022X

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p> <italic>Introduction</italic>: Recurrent urinary tract infection (UTI) is one of the major health problems in children because of its high rate of occurrence. <italic>Objective:</italic> Our aim of the study was to evaluate the prevalence and determine risk factors of recurrent UTI in Thai children. <italic>Patients and Methods</italic>: The medical records of children aged less than 15 years diagnosed with UTI at the Department of Pediatrics, Songklanagarind Hospital were reviewed. <italic>Results</italic>: A total of 307 children (144 boys, 163 girls) were followed up for at least 1 year. Fifty-six children, 31 (19.0%) boys and 25 (17.4%) girls, developed at least one recurrence totaling 153 recurrent UTI episodes. The recurrence rate was not statistically different between the sexes (<italic>p </italic> = 0.8). On multivariate analysis, genitourinary system (GU) anomalies, particularly vesicoureteral reflux (VUR), were the most significant risk factors. Children aged greater than 5 years had a slightly higher risk of recurrence, irrespective of gender. Comparison of organisms associated with recurrent UTI with those associated with first UTI showed that the prevalence of <italic>Escherichia coli</italic> decreased from 76.9% to 56.2% but was still the major causative agent. In contrast, the prevalence of <italic>Klebsiella pneumoniae</italic> and unusual or mixed organisms significantly increased from 7.8% to 15.0% and 6.2% to 16.3%, respectively. <italic>Conclusion</italic>: One-fifth of children who had UTI developed recurrence and the rates were similar for males and females. Independent risk factors for recurrent UTI were found to be at age of >5 years and underlying disease of either GU anomaly or VUR.</p> </abstract>