Impact of obesity on uvulopalatopharyngoplasty success in patients with severe obstructive sleep apnea: a retrospective single-center study in Taiwan. (March 2013)

• Record Type: Journal Article
• Authors: Shie, Dung-Yun; Tsou, Yung-An; Tai, Chih-Jaan; Tsai, Ming-Hsui
• Is Part Of: Acta oto-laryngologica. Volume 133:Number 3(2013)
• Page Start: 261
• Page End: 269
• Publication Date: 2013-03
• Subjects: Otolaryngology -- Periodicals; Ear -- Diseases -- Periodicals; Throat -- Diseases -- Periodicals; Otolaryngology -- Electronic Resources; Otorhinolaryngologic Diseases; 617.8
• DOI: 10.3109/00016489.2012.741328
• Languages: English
• ISSNs: 0001-6489

Abstract

<abstract> <title>Abstract</title> <p> <italic>Conclusion:</italic> Our findings suggest that, in Asian patients with severe obstructive sleep apnea (OSA), obesity is a better predictor of uvulopalatopharyngoplasty (UPPP) failure than Friedman stage III. <italic>Objectives:</italic> This study evaluated UPPP success rates in obese and non-obese Asian patients treated for severe OSA. <italic>Methods:</italic> Records of patients who underwent UPPP for treatment of OSA were retrospectively reviewed. Preoperative and postoperative apnea/hypopnea index (AHI) and Epworth Sleepiness Scale (ESS) score, and Friedman stage were compared in non-obese (body mass index (BMI) &lt;27 kg/m²) and obese (BMI ≥27 kg/m²) patients. Treatment success was defined as &gt;50% reduction in preoperative AHI or postoperative AHI of &lt;20 events/h. <italic>Results:</italic> Treatment success was significantly lower (<italic>p</italic> &lt; 0.0001) in the obese group (24.6%) compared with the non-obese group (62.5%). After adjusting for gender, age, BMI, Friedman stage, and preoperative AHI and ESS score, obesity was a significant independent negative predictor of treatment success (adjusted OR = 0.297, 95% CI = 0.114–0.773, <italic>p</italic> = 0.013).</p> </abstract>