Diagnosis of acute tonsillopharyngitis in primary care: a new approach for low-resource settings. (1st June 2013)

• Record Type: Journal Article
• Authors: Alper, Zuleyha; Uncu, Yesim; Akalin, Halis; Ercan, Ilker; Sinirtas, Melda; Bilgel, Nazan Gonul
• Is Part Of: Journal of chemotherapy. Volume 25:Number 3(2013:Jun.)
• Page Start: 148
• Page End: 155
• Publication Date: 2013-06-01
• Subjects: Chemotherapy -- Periodicals; Drug Therapy -- Periodicals; 615.58
• DOI: 10.1179/1973947813Y.0000000071
• Languages: English
• ISSNs: 1120-009X

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Background:</bold> Diagnosing GABHS (Group A-beta Hemolytic Streptococcus) tonsillopharyngitis by clinical scoring is a recommended approach in developed countries, but there is still much controversy for low resource settings.</p> <p> <bold>Aim:</bold> We aimed to assess the impact of Centor criteria with the support of practical laboratory tests.</p> <p> <bold>Methods:</bold> We prospectively included patients complaining sore throat (<italic>N</italic> = 282). We evaluated them in terms of Centor scoring and performed white blood cell count (WBC), C-reactive protein (CRP), rapid antigen detecting test, and throat culture.</p> <p> <bold>Results:</bold> In GABHS cases (<italic>N</italic> = 32, 11·3%), two of the criteria were observed to be positive in more than half of the cases (<italic>N</italic> = 19, 59·3%), while 13 (40·7%) cases met three/four criteria. The specificity of having two criteria was found to be 65·5% and increased to 91·5% after including CRP and WBC.</p> <p> <bold>Conclusion:</bold> Centor criteria could be safely used to reduce unnecessary antibiotic usage for tonsillopharyngitis in developing countries.</p> </abstract>