Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit (PREBIS study data). (23rd August 2012)

• Record Type: Journal Article
• Authors: Grande, I.; Goikolea, J. M.; de Dios, C.; González‐Pinto, A.; Montes, J. M.; Saiz‐Ruiz, J.; Prieto, E.; Vieta, E.
• Is Part Of: Acta psychiatrica Scandinavica. Volume 127:Number 5(2013:May)
• Page Start: 403
• Page End: 411
• Publication Date: 2012-08-23
• Subjects: Psychiatry -- Periodicals; 616.89
• DOI: 10.1111/acps.12003
• Languages: English
• ISSNs: 0001-690X

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Grande I, Goikolea JM, de Dios C, González‐Pinto A, Montes JM, Saiz‐Ruiz J, Prieto E, Vieta E, for the PREBIS group. Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit PREBIS study data).</p> <p> <bold>Objective: </bold> Patients diagnosed with bipolar disorder (BD) are reported to have significant work impairment during interepisode intervals. This study was carried out to assess potential predictors of occupational disability in a longitudinal follow‐up of euthymic patients.</p> <p> <bold>Method: </bold> We included 327 euthymic patients diagnosed with BD type I or type II, 226 of whom were employed and 101 were receiving a severe disablement benefit (SDB). Sociodemographic data were studied and episode recurrence was assessed along a 1‐year follow‐up. Logistic regression analysis was applied to determine predictors of receiving SDB. Cox regression was built to study recurrences.</p> <p> <bold>Results: </bold> Predictors of receiving SDB were: axis II comorbidity [Odds Ratio (OR) = 2.94, CI: 1.26–6.86, <italic>P</italic> = 0.013], number of manic episodes (OR = 1.21, CI: 1.10–1.34, <italic>P</italic> < 0.001), being without stable partner (OR = 2.44, CI: 1.34–4.44, <italic>P</italic> = 0.004) and older age (OR = 1.08, CI: 1.05–1.12, <italic>P</italic> < 0.001). Bipolar patients receiving SDB presented more episodic recurrences regardless of polarity than employed bipolar patients (<italic>P</italic> = 0.002). The time until recurrence in 25% of the bipolar patients receiving SDB was 6.08 months (CI: 4.44–11.77) being 13.08 months (CI: 9.60 to –) in the employed group.</p> <p> <bold>Conclusion: </bold> Occupational disability in bipolar patients is associated with axis II comorbidity, more previous manic episodes, not having a stable relationship, older age, and more recurrences at 1‐year follow‐up.</p> </abstract>