Clinical Findings and Prognostic Factors for Dogs Undergoing Cholecystectomy for Gall Bladder Mucocele. Issue 4 (17th January 2013)

• Record Type: Journal Article
• Authors: Malek, Sarah; Sinclair, Elizabeth; Hosgood, Giselle; Moens, Noel M. M.; Baily, Trina; Boston, Sarah E.
• Is Part Of: Veterinary surgery. Volume 42:Issue 4(2013)
• Page Start: 418
• Page End: 426
• Publication Date: 2013-01-17
• Subjects: Veterinary surgery -- Periodicals; Veterinary Medicine -- Periodicals; Surgery -- Periodicals; Societies, Medical -- Periodicals; 636.0897
• DOI: 10.1111/j.1532-950X.2012.01072.x
• Languages: English
• ISSNs: 0161-3499

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="vsu1072-sec-0010" sec-type="section"> <title>Objective</title> <p>To report clinical findings and explore prognostic factors for dogs that had cholecystectomy for gall bladder mucocele.</p> </sec> <sec id="vsu1072-sec-0020" sec-type="section"> <title>Study Design</title> <p>Retrospective case series.</p> </sec> <sec id="vsu1072-sec-0030" sec-type="section"> <title>Animals</title> <p>Dogs (n = 43) with gall bladder mucoceles.</p> </sec> <sec id="vsu1072-sec-0040" sec-type="section"> <title>Results</title> <p>Diagnosis of gall bladder mucoceles was confirmed by histopathology and 74% were diagnosed based on preoperative abdominal ultrasonography. Intraoperative evidence of gall bladder rupture was noted in 10 dogs (23%), and 16 (37%) had evidence of previous leakage in the abdominal cavity. One dog had positive bacterial growth from the gall bladder content. The most common histopathologic findings in liver biopsies obtained at surgery were cholangiohepatitis, biliary hyperplasia, or cholestasis. Univariate analysis showed evidence of postoperative hypotension (<italic>P</italic> = .05) to be significantly negatively associated with survival. Significant difference in mean postoperative serum lactate (<italic>P</italic> = .034) and postoperative packed cell volume (<italic>P</italic> = .063) between dogs that survived and died was also noted.</p> </sec> <sec id="vsu1072-sec-0050" sec-type="section"> <title>Conclusions</title> <p>Elevations in postoperative serum lactate concentrations and immediate postoperative hypotension in dogs undergoing cholecystectomy for gall bladder mucoceles are associated with poor clinical outcome.</p> </sec> </abstract>