Fetal aneuploidy screening by maternal plasma DNA sequencing: 'False positive' due to confined placental mosaicism. (27th November 2012)

• Record Type: Journal Article
• Authors: Choi, H.; Lau, T. K.; Jiang, F. M.; Chan, M. K.; Zhang, H. Y.; Lo, P. S. S.; Chen, F.; Zhang, L.; Wang, W.
• Is Part Of: Prenatal diagnosis. Volume 33:Number 2(2013:Feb.)
• Page Start: 198
• Page End: 200
• Publication Date: 2012-11-27
• Subjects: Prenatal diagnosis -- Periodicals; Fetus -- Diseases -- Diagnosis -- Periodicals; Electronic journals; 618.32075
• DOI: 10.1002/pd.4024
• Languages: English
• ISSNs: 0197-3851

Abstract

<abstract abstract-type="short"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>What's already known about this topic?</bold> <list list-type="bullet"> <list-item> <p>Non‐invasive prenatal testing by maternal plasma DNA sequencing is highly sensitive and specific in detecting fetal aneuploidies.</p> </list-item> </list> </p> <p> <bold>What does this study add?</bold> <list list-type="bullet"> <list-item> <p>We report a case of 'false positive' result of NIPT because of confined placental mosaicism.</p> </list-item> </list> </p> </abstract>