PAMAM dendrimer roles in gene delivery methods and stem cell research. (18th March 2013)

• Record Type: Journal Article
• Authors: Daneshvar, Nasibeh; Abdullah, Rasedee; Shamsabadi, Fatemeh T.; How, Chee Wun; MH, M. Aizat; Mehrbod, Parvaneh
• Is Part Of: Cell biology international. Volume 37:Number 5(2013)
• Page Start: 415
• Page End: 419
• Publication Date: 2013-03-18
• Subjects: Cytology -- Periodicals; Cells -- Periodicals; 571.605
• DOI: 10.1002/cbin.10051
• Languages: English
• ISSNs: 1065-6995

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <sec id="cbin10051-sec-0001" sec-type="section"> <p>Nanotechnology has provided new technological opportunities, which could help in challenges confronting stem cell research. Polyamidoamine (PAMAM) dendrimers, a new class of macromolecular polymers with high molecular uniformity, narrow molecular distribution specific size and shape and highly functionalised terminal surface have been extensively explored for biomedical application. PAMAM dendrimers are also nanospherical, hyperbranched and monodispersive molecules exhibiting exclusive properties which make them potential carriers for drug and gene delivery.</p> </sec> </abstract>