ToF‐SIMS imaging of a polymer microarray prepared using ink‐jet printing of acrylate monomers. (15th May 2012)

• Record Type: Journal Article
• Authors: Celiz, Adam D.; Hook, Andrew L.; Scurr, David J.; Anderson, Daniel G.; Langer, Robert; Davies, Martyn C.; Alexander, Morgan R.
• Is Part Of: Surface and interface analysis. Volume 45:Number 1(2013:Jan.)
• Page Start: 202
• Page End: 205
• Publication Date: 2012-05-15
• Subjects: Surfaces (Physics) -- Periodicals; Surface chemistry -- Periodicals; Thin films -- Periodicals; 541.33
• DOI: 10.1002/sia.5042
• Languages: English
• ISSNs: 0142-2421

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Polymer microarrays are a powerful sample format for high‐throughput materials discovery. We describe a polymer microarray prepared via ink‐jet printing for the purpose of screening novel biomaterials. Ink‐jet printing has advantages over other printing techniques including avoiding contact with the surface, preventing damage to fragile substrates, and the control of the drop volume to control the amount of material deposited. We investigate a method for ink‐jet printing a library of monomer solutions, which are subsequently polymerized <italic>in</italic>‐situ to form the polymer microarray. Imaging of the polymer microarray using time‐of‐flight secondary ion mass spectrometry is employed to map specific ions characteristic of the constituent monomers and identify which chemical functionalities are present at the surface of each polymer. This is particularly important in determining the quality of the array and understanding the interactions that occur at the interface between a material and a biological organism. Copyright © 2012 John Wiley &amp; Sons, Ltd.</p> </abstract>