Kidney grafts from donors ≤5 yr of age: Single kidney transplantation for pediatric recipients or en bloc transplantation for adults?. (26th February 2013)

• Record Type: Journal Article
• Authors: Gallinat, Anja; Sotiropoulos, Georgios C.; Witzke, Oliver; Treckmann, Jürgen W.; Molmenti, Ernesto P.; Paul, Andreas; Vester, Udo
• Is Part Of: Pediatric transplantation. Volume 17:Number 2(2013:Mar.)
• Page Start: 179
• Page End: 184
• Publication Date: 2013-02-26
• Subjects: Transplantation of organs, tissues, etc. in children -- Periodicals; 617.95408305
• DOI: 10.1111/petr.12049
• Languages: English
• ISSNs: 1397-3142

Abstract

<abstract abstract-type="main" xml:lang="en" id="petr12049-abs-0001"> <title>Abstract</title> <sec id="petr12049-sec-0001" sec-type="section"> <p>Kidneys from donors ≤5 yr of age represent a controversial issue. The purpose of this study was to compare the transplant outcomes as single and single/en bloc grafts into pediatric and adult KT recipients, respectively. All recipients of kidneys from donors ≤5 yr old transplanted at our institution from 3/2003 to 12/2010 were evaluated, and corresponding data were analyzed. There were 11 pediatric and 14 adult recipients. Median donor age and body weight were 38 months and 14 kg, respectively. PNF, n = 2 and DGF, n = 1 were observed only among adult recipients. Five‐yr graft survival was 100% for children and 86% for adults. There were no significant differences in graft and patient survival, PNF, DGF, acute rejection, or postoperative complications among children/single (n = 10), adults/en bloc (n = 10), and adults/single (n = 4) KT. Major complications were documented in six adult recipients and one pediatric recipient after en bloc KT. Pediatric recipients showed significantly higher GFR during the first post‐transplant year. Kidneys from donors ≤5 yr of age have at least as good outcomes as when transplanted as single allografts into children. Although the study‐volume is small, it seems that children benefit from a pediatric‐oriented allocation policy.</p> </sec> </abstract>