Candidaemia in internal medicine departments: the burden of a rising problem. (15th February 2013)

• Record Type: Journal Article
• Authors: Bassetti, M.; Molinari, M. P.; Mussap, M.; Viscoli, C.; Righi, E.; Roilides, E.
• Is Part Of: Clinical microbiology and infection. Volume 19:Number 6(2013:Jun.)
• Page Start: E281
• Page End: E284
• Publication Date: 2013-02-15
• Subjects: Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1111/1469-0691.12155
• Languages: English
• ISSNs: 1198-743X

Abstract

<abstract abstract-type="main" id="clm12155-abs-0001"> <title>Abstract</title> <p>Although internal medicine wards (IMWs) represent a significant reservoir of patients with candidemia, few investigators have specifically addressed the epidemiological aspects of candidaemia in this population. Of all patients hospitalized during the study period with candidaemia, 133/348 (38%) were admitted to IMWs. Variables associated with IMWs included: antibiotic therapy prior to hospitalization, urinary or central venous catheter, parenteral nutrition, tumour and age &gt;75 years. Overall, 30‐day mortality in IMWs was significantly higher than that in other wards (51.1% vs. 38.2%, p &lt;0.02).</p> <p>Multiple logistic regression analysis identified the administration of antifungal treatment 48 h after having the first positive BC as an independent determinant of hospital mortality.</p> <p>Patients with candidaemia in IMWs account for a substantial proportion of patients with candidaemia and have higher mortality compared with patients in other wards.</p> </abstract>