The Relationship between Morning Hypertension and Sleep Quality in Patients with Obstructive Sleep Apnea Syndrome. (July 2013)

• Record Type: Journal Article
• Authors: Sasaki, Nobuo; Ozono, Ryoji; Yamauchi, Ryo; Teramen, Kazushi; Edahiro, Yoshinobu; Ishii, Kiyomi; Seto, Ayako; Kihara, Yasuki
• Is Part Of: Clinical and experimental hypertension. Volume 35:Number 4(2013)
• Page Start: 250
• Page End: 256
• Publication Date: 2013-07
• Subjects: Hypertension -- Chemotherapy -- Periodicals; Hypotensive agents -- Periodicals; 616.132
• DOI: 10.3109/10641963.2013.780069
• Languages: English
• ISSNs: 1064-1963

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>This study aimed to investigate the prevalence of abnormal diurnal blood pressure (BP) profiles in patients with obstructive sleep apnea syndrome (OSAS) in relation to the data of a sleep study. Total 103 patients newly diagnosed with OSAS underwent overnight polysomnography and 24-hour ambulatory BP measurements. Patients without morning or nocturnal hypertension (control group), patients with morning hypertension but not nocturnal hypertension (surge-type group), and patients with both morning and nocturnal hypertension (sustained-type group) were compared. Morning hypertension was present in 54 patients (16 surge-type and 38 sustained-type). The apnea–hypopnea index and sleep efficiency were higher and lower, respectively, in the sustained-type group than in the other groups. Slow-wave sleep incidence was significantly lower in the sustained-type and surge-type groups than in the control group. These results suggest that approximately half the OSAS patients displayed morning hypertension, the sustained-type being more common than the surge-type. Poor sleep quality plays an important role in the pathogenesis of morning hypertension in both the sustained- and the surge-type group.</p> </abstract>