Cephalosporin resistant Escherichia coli from cancer patients in Cairo, Egypt. (14th May 2013)

• Record Type: Journal Article
• Authors: Abdelaziz, Mohammed O.; Bonura, Celestino; Aleo, Aurora; Fasciana, Teresa; Calà, Cinzia; Mammina, Caterina
• Is Part Of: Microbiology and immunology. Volume 57:Number 5(2013:May)
• Page Start: 391
• Page End: 395
• Publication Date: 2013-05-14
• Subjects: Microbiology -- Periodicals; Immunology -- Periodicals; Allergy and Immunology -- Periodicals; Microbiology -- Periodicals; Microbiologie -- Périodiques; Immunologie -- Périodiques; 579
• DOI: 10.1111/1348-0421.12046
• Languages: English
• ISSNs: 0385-5600

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>ABSTRACT</title> <sec id="mim12046-sec-0001" sec-type="section"> <p>Cephalosporin‐resistant <italic>Escherichia coli</italic> has been increasingly reported worldwide. In this study, 32 cephalosporin resistant <italic>E. coli</italic> isolates identified from cancer patients in Cairo, Egypt in 2009–2010 were analyzed. Twenty‐three were of phylogenetic group D, seven A and one each B1 and B2. By rep‐PCR 15 phylogroup D isolates were grouped in four clusters, one with sequence type (ST) 405 and three ST68. Seventeen isolates showed single patterns. <italic>bla</italic>_CTX‐M‐15 and <italic>aac</italic>(<italic>6</italic>')<italic>‐Ib‐cr</italic> were the most common resistance determinants. <italic>bla</italic>_OXA‐48 and <italic>bla</italic>_VIM were also detected. Multidrug resistant <italic>E. coli</italic> seriously affects healthcare, especially in immunocompromised hosts, such as cancer patients.</p> </sec> </abstract>