Growth of a solitary pulmonary nodule after 6 years diagnosed as oncocytic carcinoid tumour with a high 18‐fluorodeoxyglucose (18F‐FDG) uptake in positron emission tomography‐computed tomography (PET‐CT). (16th January 2012)

• Record Type: Journal Article
• Authors: Turan, Onur; Ozdogan, Ozhan; Gurel, Duygu; Onen, Ahmet; Kargi, Aydanur; Sevinc, Can
• Is Part Of: Clinical respiratory journal. Volume 7:Number 1(2013)
• Page Start: e1
• Page End: e5
• Publication Date: 2012-01-16
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiratory organs -- Periodicals; 616.24
• DOI: 10.1111/j.1752-699X.2011.00274.x
• Languages: English
• ISSNs: 1752-6981

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p> <bold>Introduction: </bold> Pulmonary carcinoid tumour is low‐grade neuroendocrine malignancy that is seen 1%–2% of all lung neoplasms. Oncocytic carcinoid type is a rarely seen variant of pulmonary carcinoids. As carcinoid tumours have hypometabolic activity, they usually have lower 18‐fluorodeoxyglucose (18F‐FDG) uptake than expected for lung carcinoma on positron emission tomography (PET).</p> <p> <bold>Case Report: </bold> A 45‐year‐old non‐smoking man had a stable solitary pulmonary nodule followed for 6 years; the tumour remained the same size (1.5 × 2.4 cm) during this period. The patient was admitted to the hospital with complaints of repetitive sneezing and rhinorrhoea. He also experienced flushing and bronchospasm. His chest X‐ray revealed a minimal increase in the size of the solitary pulmonary nodule (2.0 × 2.8 cm). In PET‐computed tomography (CT), the parenchymal nodule in the anterior segment of the right lung had a standard uptake value of 38.0 mg/mL, which was interpreted as a malignant nodule. He underwent fibre‐optic bronchoscopy, but cytology showed no evidence of malignancy. Right upper and middle bilobectomy was performed, and a pulmonary carcinoid tumour with an oncocytic subgroup was diagnosed. The diagnosis of carcinoid syndrome was further confirmed by an elevated 24‐h urinary excretion of 5‐hydroxyindoleacetic acid.</p> <p> <bold>Conclusion: </bold> We present a rare case of an oncocytic carcinoid tumour with an increase in the size of a solitary pulmonary nodule after 6 years' follow‐up. In addition, PET‐CT showed a very high 18F‐FDG uptake in this patient, which is an unexpected finding with a pulmonary carcinoid tumour.</p> <p>Please cite this paper as: Turan O, Ozdogan O, Gurel D, Onen A, Kargi A and Sevinc C. Growth of a solitary pulmonary nodule after 6 years diagnosed as oncocytic carcinoid tumour with a high 18F‐FDG uptake in positron emission tomography‐computed tomography (PET‐CT). <italic>Clin Respir J</italic> 2013; 7: e1–e5.</p> </abstract>