MAIGO2 is involved in abscisic acid‐mediated response to abiotic stresses and Golgi‐to‐ER retrograde transport. Issue 2 (1st November 2012)

• Record Type: Journal Article
• Authors: Zhao, Pengshan; Liu, Fei; Zhang, Bo; Liu, Xin; Wang, Bing; Gong, Jiao; Yu, Guanzhong; Ma, Miao; Lu, Yujian; Sun, Jing; Wang, Zhenyu; Jia, Pengfei; Liu, Heng
• Is Part Of: Physiologia plantarum. Volume 148:Issue 2(2013:Jun.)
• Page Start: 246
• Page End: 260
• Publication Date: 2012-11-01
• Subjects: Plant physiology -- Periodicals; 571.2
• DOI: 10.1111/j.1399-3054.2012.01704.x
• Languages: English
• ISSNs: 0031-9317

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The central role of multisubunit tethering complexes in intracellular trafficking has been established in yeast and mammalian systems. However, little is known about their roles in the stress responses and the early secretory pathway in <italic>Arabidopsis</italic>. In this study, Maigo2 (MAG2), which is equivalent to the yeast Tip20p and mammalian Rad50‐interacting protein, is found to be required for the responses to salt stress, osmotic stress and abscisic acid in seed germination and vegetative growth, and MAG2‐like (MAG2L) is partially redundant with MAG2 in response to environmental stresses. MAG2 strongly interacts with the central region of ZW10, and both proteins are important as plant endoplasmic reticulum (ER)‐stress regulators. ER morphology and vacuolar protein trafficking are unaffected in the <italic>mag2</italic>, <italic>mag2l</italic> and <italic>zw10</italic> mutants, and the secretory marker to the apoplast is correctly transported in <italic>mag2</italic> plants, which indicate that MAG2 functions as a complex with ZW10, and is potentially involved in Golgi‐to‐ER retrograde trafficking. Therefore, a new role for ER–Golgi membrane trafficking in abiotic‐stress and ER‐stress responses is discovered.</p> </abstract>