The effect of mate tea (Ilex paraguariensis) on metabolic and inflammatory parameters in high-fat diet-fed Wistar rats. (August 2013)

• Record Type: Journal Article
• Authors: Borges, Maria Carolina; Vinolo, Marco Aurélio Ramirez; Nakajima, Karina; de Castro, Inar Alves; Bastos, Deborah Helena Markowicz; Borelli, Primavera; Fock, Ricardo Ambrósio; Tirapegui, Julio; Curi, Rui; Rogero, Marcelo Macedo
• Is Part Of: International journal of food sciences and nutrition. Volume 64:Number 5(2013)
• Page Start: 561
• Page End: 569
• Publication Date: 2013-08
• Subjects: Food -- Analysis -- Periodicals; Nutrition -- Periodicals; 641.3
• DOI: 10.3109/09637486.2012.759188
• Languages: English
• ISSNs: 0963-7486

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>This study investigated the effects of mate tea (<italic>Ilex paraguariensis</italic>) aqueous extract consumption on metabolic indicators and inflammatory response of peritoneal macrophages in rats fed a high-fat diet (HFD). Male Wistar rats were fed a control diet or a HFD for 12 weeks. At the end of this period, rats received, or not, daily doses of yerba maté for 4 weeks. The consumption of yerba maté promoted weight loss, attenuated the HFD-detrimental effects on adiposity and insulin sensitivity and decreased blood levels of the inflammatory biomarkers (<italic>p</italic> &lt; 0.05). Concerning peritoneal macrophages, mate tea consumption decreased the production of interleukin (IL)-6, but did not influence the production of IL-1β, tumour necrosis factor-α and nitric oxide; cytokine mRNA expression; or the activation of the nuclear factor-κB signalling pathway. In summary, the consumption of mate tea had no consistent effect in the inflammatory response of peritoneal macrophages, but reduced cardiometabolic risk markers.</p> </abstract>