Effect of experimental feed additives on aflatoxin in milk of dairy cows fed aflatoxin‐contaminated diets. Issue 4 (7th June 2012)

• Record Type: Journal Article
• Authors: Kissell, L.; Davidson, S.; Hopkins, B. A.; Smith, G. W.; Whitlow, L. W.
• Is Part Of: Journal of animal physiology and animal nutrition. Volume 97:Issue 4(2013:Aug.)
• Page Start: 694
• Page End: 700
• Publication Date: 2012-06-07
• Subjects: Animal nutrition -- Periodicals; Feeds -- Periodicals; 636.085
• DOI: 10.1111/j.1439-0396.2012.01311.x
• Languages: English
• ISSNs: 0931-2439

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Summary</title> <p>Three studies were conducted to determine the potential of experimental feed additives (EFAs), clays or non‐digestible yeast oligosaccharides, to reduce milk aflatoxin (AFM<sub>1</sub>) concentrations in lactating Holstein cows consuming aflatoxin‐contaminated diets. All studies included a pre‐treatment period and a 2‐week experimental period in a randomized block design. During the pre‐treatment period, cows received a total mixed ration (TMR) with no aflatoxin contamination. During both experimental weeks, all cows were fed a TMR containing aflatoxin‐contaminated corn. During experimental week 1, cows received no EFA's in the TMR, but EFA's were included in the TMR for the second experimental week. In studies 1 and 2, the experimental period consisted of 2 weeks each lasting 7 days with 12 cows per treatment. Aflatoxin M<sub>1</sub> concentrations were analysed by HPLC for milk samples collected on days 5–7 and days 11–14. In various experiments, treatments included control (no EFA), 100 g/cow daily of experimental Lallemand<sup>®</sup> product, 10 g/cow daily of MTB‐100<sup>®</sup>‐2004, (Alltech, Inc.), 10 g/cow daily of MTB‐100<sup>®</sup>‐2006, (Alltech, Inc.), 10 g/cow daily of experimental Alltech<sup>®</sup> product (Alltech, Inc.) and 227 g/cow daily of Astra‐Ben 20<sup>®</sup> (AB‐20<sup>®</sup>; Prince Agri Products, Inc.). In study 3, the experimental period of 2 weeks each lasting 8 days and milk samples were collected from day 4 to 8 and day 11 to 16. Milk samples from study 3 were analysed for AFM<sub>1</sub> concentrations by ELISA. For all experiments, changes in AFM<sub>1</sub> concentrations because of the addition of EFA's were calculated. Four of the five EFAs tested in this study had no significant effect on AFM<sub>1</sub> concentrations. However, the addition of AB‐20<sup>®</sup> resulted in a significant decrease in AFM<sub>1</sub> concentrations (60.4%). In summary, the addition of AB‐20<sup>®</sup> to the diet of cattle appears to be effective for significantly reducing AFM<sub>1</sub> concentrations in the milk of cows fed an aflatoxin‐contaminated diet.</p> </abstract>