Resolution of Coccidioides immitis Endophthalmitis with an Aggressive Surgical and Medical Therapeutic Approach. (July 2013)

• Record Type: Journal Article
• Authors: Reed, David C.; Shah, Kayur H.; Hubschman, Jean-Pierre
• Is Part Of: Seminars in ophthalmology. Volume 28:Number 4(2013)
• Page Start: 251
• Page End: 252
• Publication Date: 2013-07
• Subjects: Ophthalmology -- Periodicals; Eye -- Diseases -- Periodicals; Eye -- Surgery -- Periodicals; 617.7005
• DOI: 10.3109/08820538.2013.788677
• Languages: English
• ISSNs: 0882-0538

Abstract

<abstract> <title>Abstract</title> <p> <italic>Introduction</italic>: <italic>Coccidioides immitis</italic> endophthalmitis usually results in enucleation, and there is evidence that vitrectomized eyes are more likely to become enucleated. <italic>Methods</italic>: A 55-year-old man presented to us with steroid-resistant granulomatous uveitis and was eventually diagnosed with <italic>C. immitis</italic> endophthalmitis. He was treated with an aggressive medical and surgical approach, receiving a total of 16 intravitreal antifungal injections and three vitrectomies, as well as lensectomy and penetrating keratoplasty. <italic>Results</italic>: At 13 months after presentation, the patient's eye was free of inflammation, and his best corrected visual acuity was 20/25. <italic>Discussion</italic>: This is the first reported case of culture-proven <italic>C. immitis</italic> endophthalmitis with a favorable final outcome. We propose that the good outcome may have been due to our aggressive therapeutic approach.</p> </abstract>