Markers for severity of illness associated with decreased snoring in toddlers born ELGA. (1st November 2012)

• Record Type: Journal Article
• Authors: Wang, Katherine; DiFiore, Juliann M; Martin, Richard J; Rosen, Carol L; Hibbs, Anna Maria
• Is Part Of: Acta pædiatrica. Volume 102:Number 1(2013:Jan.)
• Page Start: e39
• Page End: e43
• Publication Date: 2012-11-01
• Subjects: Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.12033
• Languages: English
• ISSNs: 0803-5253

Abstract

<abstract abstract-type="main" xml:lang="en" id="apa12033-abs-0001"> <title>Abstract</title> <sec id="apa12033-sec-0001" sec-type="section"> <title>Aim</title> <p>To describe the prevalence of paediatric sleep disordered breathing (SDB) symptoms in extremely low gestational age infants and identify neonatal risk factors, including early exposure to hypoxia and hyperoxia.</p> </sec> <sec id="apa12033-sec-0002" sec-type="section"> <title>Methods</title> <p>Patients <28 weeks gestation were monitored with high‐resolution pulse oximetry. Hypoxia/hyperoxia variables were defined as percentage time of first 4 weeks of life that SaO<sub>2</sub> < 80% or SaO<sub>2</sub> > 98%, respectively. Parents completed part of the OSA‐18 questionnaire for symptoms of SDB at 18–22 months. Logistic regression was used to test the association between risk factors and sleep symptoms.</p> </sec> <sec id="apa12033-sec-0003" sec-type="section"> <title>Results</title> <p>Of 182 patients recruited, 138 (76%) completed the questionnaire. The mean gestation was 26 weeks, and mean birth weight 887 grams. Loud snoring (21%) and restless sleep (24%) were the most prevalent symptoms. Female sex was associated with an increased risk of loud snoring (OR, 2.7; CI, 1.13–6.5). Prolonged mechanical ventilation, necrotizing enterocolitis and prolonged caffeine use, however, were inversely correlated with loud snoring. Neither neonatal hypoxia nor hyperoxia were associated with sleep symptoms.</p> </sec> <sec id="apa12033-sec-0004" sec-type="section"> <title>Conclusions</title> <p>While the prevalence of sleep disordered breathing symptoms is similar to reported rates, we found a sex difference not previously reported. Interestingly, markers for severity of illness show a pattern of being protective against loud snoring.</p> </sec> </abstract>