Association of Arterial Stiffness With Obesity in Australian Women: A Pilot Study. Issue 2 (28th November 2012)

• Record Type: Journal Article
• Authors: Pal, Sebely; Radavelli‐Bagatini, Simone
• Is Part Of: Journal of clinical hypertension. Volume 15:Issue 2(2013:Feb.)
• Page Start: 118
• Page End: 123
• Publication Date: 2012-11-28
• Subjects: Hypertension -- Periodicals; 616.132
• DOI: 10.1111/jch.12038
• Languages: English
• ISSNs: 1524-6175

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>This study investigated the arterial stiffness status in overweight/obese Australian women compared with their lean counterparts. Twenty‐six Caucasian women were designated into one of two groups: overweight/obese (body mass index [BMI] 25–34.9 kg/m<sup>2</sup>[ n=12]) and lean (BMI 18.5–24.9 kg/m<sup>2</sup> [n=14]) groups. Participants were assessed for clinical, anthropometric, metabolic, and augmentation index (AIx) measurements. Age was similar between groups (<italic>P</italic>=.482). BMI was significantly higher in overweight/obese compared with lean participants (30.26±1.09 vs 21.62±0.52 kg/m<sup>2</sup>, <italic>P</italic>=.001) as well as the percentage of body fat (40.60±2.43 vs 21.57±1.13, <italic>P</italic>=.001), waist circumference (91.47±2.77 vs 70.67±1.60, <italic>P</italic>=.001), and waist/hip ratio (0.81±0.04 vs 0.71±0.03, <italic>P</italic>=.036). Overweight/obese group showed higher total cholesterol, triglyceride, low‐density lipoprotein cholesterol, and fasting glucose levels compared with the lean group (all <italic>P</italic><.05). Both systolic (122.92±3.18 mm Hg vs 108.14±2.42 mm Hg, <italic>P</italic>=.001) and diastolic (83.58±2.43 mm Hg vs 72.43±1.29 mm Hg, <italic>P</italic>=.0001) blood pressures, as well as AIx (50.08±4.7 vs 120.79±2.17, <italic>P</italic>=.001) were significantly higher in the overweight/obese group compared with the lean group. AIx was positively associated with measurements of body composition (<italic>P</italic><.05), triglycerides (<italic>r</italic>=0.361, <italic>P</italic>=.035) and glucose levels (<italic>r</italic>=0.371, <italic>P</italic>=.031), and systolic and diastolic blood pressure (<italic>r</italic>=0.793 and <italic>r</italic>=0.718, respectively; <italic>P</italic>=.0001). This data suggests that arterial stiffness is associated with obesity, along with other metabolic abnormalities in Australian women. <italic>J Clin Hypertens (Greenwich). 2012;00:00–00.</italic>©2012 Wiley Periodicals, Inc.</p> </abstract>