The risk of placenta accreta following primary elective caesarean delivery: a case–control study. Issue 7 (28th February 2013)

• Record Type: Journal Article
• Authors: Kamara, M; Henderson, JJ; Doherty, DA; Dickinson, JE; Pennell, CE
• Is Part Of: BJOG. Volume 120:Issue 7(2013:Jul.)
• Page Start: 879
• Page End: 886
• Publication Date: 2013-02-28
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; 618
• DOI: 10.1111/1471-0528.12148
• Languages: English
• ISSNs: 1470-0328

Abstract

<abstract abstract-type="main" id="bjo12148-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="bjo12148-sec-0001" sec-type="section"> <title>Objective</title> <p>To evaluate the risk of placenta praevia accreta following primary (first) elective or primary emergency caesarean section in a pregnancy complicated by placenta praevia.</p> </sec> <sec id="bjo12148-sec-0002" sec-type="section"> <title>Design</title> <p>Retrospective matched case–control study, employing variable matching.</p> </sec> <sec id="bjo12148-sec-0003" sec-type="section"> <title>Setting</title> <p>Tertiary referral centre between 1993 and 2008.</p> </sec> <sec id="bjo12148-sec-0004" sec-type="section"> <title>Population</title> <p>Sixty‐five cases and 102 controls were used for the analysis from a total of 82 667 births during the study period.</p> </sec> <sec id="bjo12148-sec-0005" sec-type="section"> <title>Methods</title> <p>Relevant data were abstracted from clinical records. Matching of cases with controls was based on co‐existing placenta praevia, number of previous caesarean sections, and age, with one or two controls per case. Results are presented as odds ratios (ORs) with 95% confidence intervals (95% CIs).</p> </sec> <sec id="bjo12148-sec-0006" sec-type="section"> <title>Main outcome measures</title> <p>Placenta accreta in a pregnancy complicated by placenta praevia following a primary elective or emergency caesarean section, and morbidity associated with pregnancies complicated by placenta accreta.</p> </sec> <sec id="bjo12148-sec-0007" sec-type="section"> <title>Results</title> <p>Significantly more cases than controls had an elective caesarean section for their primary caesarean delivery (46.2 versus 18.6%; <italic>P </italic>< 0.001). There were no differences between groups for previous pregnancy loss, uterine surgery, and vaginal delivery, before or after the primary caesarean section. Compared with primary emergency caesarean section, primary elective caesarean section significantly increased the risk of placenta accreta in a subsequent pregnancy in the presence of placenta praevia (OR 3.00; 95% CI 1.47–6.12; <italic>P</italic> = 0.025).</p> </sec> <sec id="bjo12148-sec-0008" sec-type="section"> <title>Conclusions</title> <p>Our results suggest that women with a primary elective caesarean section without labour are more likely, compared with those undergoing primary emergency caesarean section with labour, to develop an accreta in a subsequent pregnancy with placenta praevia.</p> </sec> </abstract>