Small animal positron emission tomography imaging and in vivo studies of atherosclerosis. (2nd January 2013)

• Record Type: Journal Article
• Authors: Hag, Anne Mette Fisker; Ripa, Rasmus Sejersten; Pedersen, Sune Folke; Bodholdt, Rasmus Poul; Kjaer, Andreas
• Is Part Of: Clinical physiology and functional imaging. Volume 33:Number 3(2013:May)
• Page Start: 173
• Page End: 185
• Publication Date: 2013-01-02
• Subjects: Physiology, Pathological -- Periodicals; Diagnostic imaging -- Periodicals; 612
• DOI: 10.1111/cpf.12017
• Languages: English
• ISSNs: 1475-0961

Abstract

<abstract abstract-type="main" id="cpf12017-abs-0001"> <title>Summary</title> <p>Atherosclerosis is a growing health challenge globally, and despite our knowledge of the disease has increased over the last couple of decades, many unanswered questions remain. As molecular imaging can be used to visualize, characterize and measure biological processes at the molecular and cellular levels in living systems, this technology represents an opportunity to investigate some of these questions <italic>in vivo</italic>. In addition, molecular imaging may be translated into clinical use and eventually pave the way for more personalized treatment regimes in patients. Here, we review the current knowledge obtained from <italic>in vivo</italic> positron emission tomography studies of atherosclerosis performed in small animals.</p> </abstract>