A guide to sample size for animal-based studies. (2023)

• Record Type: Book
• Further Information: Note: Penny S. Reynolds.
• Authors: Reynolds, Penny S
• Contents: Preface Acknowledgements Part I. What is sample size? 1. Introduction: The sample size problem in animal-based research 2. Sample size basics 3. Ten strategies to increase information (and reduce animal numbers) Part II. Sample size for feasibility and pilot studies 4. Introduction to pilot studies 5. Operational pilots 6. Empirical and translational pilots 7. Feasibility calculations: Arithmetic estimation 8. Feasibility calculations: Probability-based estimation Part III. Sample size for description 9. Introduction to descriptive studies 10. Confidence intervals 11. Prediction intervals 12. Tolerance intervals 13. Reference intervals Part IV. Sample size for comparison 14. Hypothesis testing, power, non-centrality 15. A bestiary of effect sizes 16. Comparing two groups: Continuous outcomes 17. Comparing two groups: Binary and count outcomes 18. Comparing two groups: Time to event outcomes 19. Comparing multiple factors 20. Multi-level and hierarchical designs 21. Ordinal data 22. Dose-response studies Index
• Edition: 1st
• Publisher Details: Chichester : Wiley Blackwell
• Publication Date: 2023
• Extent: 1 online resource (288 pages)
• Subjects: 616.0273; Animal models in research; Clinical medicine -- Research -- Statistical methods; Sampling (Statistics)
• Languages: English
• ISBNs: 9781119799986
• Notes: Note: Includes bibliographical references and index.; Note: Description based on CIP data; resource not viewed.
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