Epigenetic cancer therapy. (2023)

• Record Type: Book
• Further Information: Note: Edited by Steven Gray.
• Editors: (Thoracic oncology researcher), Gray, Steven G
• Contents: 1. Introduction Part 1: Introduction and Key Concepts 2. DNA Methylation and Hydroxymethylation in Cancer 3. Writers, Readers, and Erasers of Epigenetic Marks 4. Oncohistones 5. MicroRNAs, epi-miRNAs and Cancer 6. Long Noncoding RNAs and Cancer 7. The Epitranscriptome 8. Mining the Epigenetic Landscape: Surface Mining or Deep Underground - Alecsandar Milosavljevic 9: Epigenetics Clocks: Concepts for Carcinogenesis10: Environmental Pollution Epigenetics and Cancer Part 2: Epigenetics and Cancer 11. Development of Epigenetic Targeted Therapies in Hematological Malignancies: From Serendipity to Synthetic Lethality 12. Epigenetic Therapy in Lung Cancer 13. Breast Cancer Epigenetics 14. Therapeutic Applications of the Prostate Cancer Epigenome 15. Neuroblastoma Part 3: Targeting Aberrant Epigenetics 16. Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches - 17. Emerging Epigenetic Therapies- Lysine Methyltransferase/PRC Complex Inhibitors 18. Inhibitors of Jumonji C-Domain Histone Demethylases 19. Emerging Epigenetic Therapies: Lysine Acetyltransferase Inhibitors 20: Histone Deacetylases 21. Emerging Epigenetic Therapies Part 4: Issues to Overcome/Areas of Concern 22. Genetic Intratumoral Heterogeneity 23. Challenges for single cell epigenetic analysis 24. Epigenetics Underpinning DNA Damage Repair 25. Epigenetics of Cisplatin Resistance 26. Therapeutically Targeting Epigenetic Regulation of Cancer Stem Cells Part 5: Future Directions: Translation to the Clinic 27. Personalized Epigenetic Therapy-Chemosensitivity Testing 28. Personalized Therapy-Epigenetic Profiling as Predictors of Prognosis and Response 29. Epigenetic Priming - Fact or Fallacy 30. CRISPR and epigenetics 31. Epigenetics and CAR-T
• Edition: Second edition
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2023
• Extent: 1 online resource (765 pages), illustrations
• Subjects: 616.994042; Cancer -- Genetic aspects; Cancer -- Treatment; Epigenesis
• Languages: English
• ISBNs: 9780323917155
• Related ISBNs: 9780323913676
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.